Chicopee police say a Pontiac Grand Prix crossed the center line, colliding with a tractor trailer.
The woman driving the Grand Prix and the driver of the truck were taken to Baystate Medical Center. Both were said to be alert and conscious when they were taken to the hospital.
Police say speed was a factor.
Granby road is closed from Chicopee to Nelson Street.
Police say the accident reconstruction unit is responding to the scene.
Granby Road is expected to be closed until at least 11 p.m.
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